Liquid Oral Plants – Liquid Oral Dosage Forms
- July 31, 2023
Bright Pharma Engineering is an advanced equipment manufacturing company specializing in the production of process equipment for the pharmaceutical, bio-pharma, healthcare, and cosmetic industries. We undertake the production of aseptic mixing vessels based on the ASME BPE guidelines, equipped with aseptic magnetic mixers and advanced instruments as per EHEDG guidelines. Our CIP modules come in a variety of types and are custom-built to clean the vessels. We understand that the cleaning of production equipment is an extremely essential part of the pharmaceutical production process, and thus it holds equal importance to the production process itself, according to FDA guidelines. The cleaning of all equipment must adhere to strict standards of documentation, and the process must be validated based on the standards laid down by the FDA. At Bright Pharma Engineering, we have a state-of-the-art system that delivers WFI of a higher quality standard for storage and distribution, surpassing the standards imposed by pharmacopeias worldwide.
Liquid manufacturing plants are highly recommended tools for the production of oral liquids in the pharmaceutical industry. These plants are specifically designed to take care of two critical factors that are directly linked to the quality of the liquid produced. The capacity of these plants ranges from 50 to 20,000 liters. The oral liquid manufacturing plant is equipped with various vessels including a sugar syrup vessel, an online sugar syrup pre-filter, a manufacturing vessel storage vessel, a vacuum system for the transfer of sugar and sugar syrup, product piping, control panels, and transfer pumps. One of the greatest benefits of utilizing this plant is effective manpower utilization.
Oral liquids are homogeneous liquid preparations, which commonly include a solution, emulsion, or suspension of one or more active ingredients in a suitable liquid base. These liquids are formulated for oral administration and are used either as such or after dilution.
We offer our Manufacturing plant as per below:
- Cough Syrup Liquid Manufacturing Plant
- Drop Solutions Liquid Manufacturing Plant
- Expectorant Liquid Manufacturing Plant
- Suspensions Liquid Manufacturing Plant
Syrup
The syrup is a liquid consumed orally that contains active ingredients in a solution, which may or may not have added sugar to inhibit crystallization. Sugarless syrups may use saccharin as a sweetening agent and a thickening agent to induce desired thickness. Ethanol (95%) may be used in syrups as a preservative or as a solvent for flavors. Antimicrobial agents may be included in the syrup to maintain its microbial quality and longevity. The base properties of the syrup may be modified based on taste alteration or solubilization requirements.
Oral Suspension
An oral suspension is a type of liquid medication that has one or more active ingredients mixed in a suitable base. Sometimes, solid particles may separate from the liquid after some time, but they can be easily dispersed again by shaking the bottle. When manufacturing oral suspensions that contain suspended particles, it is important to control the size of the particles to ensure that the medication is effective for its intended purpose. In essence, an oral suspension is a liquid form of medication that may require shaking before use to ensure that all of the ingredients are evenly distributed in the solution.
Oral Solution
An oral solution refers to a liquid that can be swallowed, made with a suitable base in which one or more active ingredients are dissolved. This liquid is intended to be taken orally and is designed to effectively deliver the active ingredients to the body.
Oral Drop
An oral Drop is an oral liquid that is prepared to take in small quantities with the help of a suitable measuring device such as a dropper.
Oral Emulsion
An oral emulsion refers to a liquid medication taken orally, which includes one or more active elements. These active ingredients are prone to instability in the water phase and hence require stabilization by oil-in-water dispersions. Dissolved solids may be present in either or both phases of the compound. Although the preparation may result in two phases that may separate, users can easily homogenize them by shaking. Once properly shaken, the preparation is fully stable, and users can take a homogeneous dose of the medication.
Mixtures
The oral liquid is a combination of active ingredients mixed with a suitable base. These ingredients can be suspended or dispersed in the liquid. However, after some time, solid particles in the mixture may settle down, but this is not a cause for concern. They can easily be mixed back into the liquid upon shaking.
Linctus
A linctus is a type of oral liquid that contains one or more medicinal substances dissolved in a suitable liquid base. Such preparations usually contain a higher proportion of sugar, particularly sucrose. Linctuses are commonly used for treating cough and can be taken directly without the need for any water.
Elixir
This is an oral liquid that is clear and flavored, composed of one or more active ingredients that are dissolved in a suitable base. The liquid has a significant amount of sucrose and may also contain ethanol in either a diluted or concentrated form, primarily 95%.
APPLICATIONS :
- Pharma Orals Dose
- Liquids Syrup
- Suspensions Syrup
- Cough Syrups
- Drop Solutions
- Expectorants Liquid
- Antacid Suspensions Liquid
